USCAP Gynecological Pathology: Essential Knowledge for Diagnostic Practice (Presidential Edition) 2026 (Videos + PDFs)

Comprehensive Update in Modern Gynecological Pathology and Diagnostic Practice

The USCAP Gynecological Pathology: Essential Knowledge for Diagnostic Practice (Presidential Edition) 2026 is an advanced educational program developed through a collaboration between the United States and Canadian Academy of Pathology and the International Society of Gynecological Pathologists. This comprehensive course provides an evidence-based review of contemporary gynecological pathology, emphasizing practical diagnostic approaches, updated disease classifications, molecular pathology, and challenging diagnostic scenarios encountered in daily practice.

Designed by internationally recognized experts, the course reflects the rapidly evolving landscape of gynecologic pathology, including emerging molecular discoveries, revised diagnostic criteria, and updates associated with the forthcoming revision of the World Health Organization Classification of Female Genital Tumours.

Format: 14 Videos + 16 PDFs
Original Release Date: March 11, 2026
Specialty: Gynecological Pathology

Course Overview

Diagnostic gynecological pathology encompasses a broad spectrum of benign, premalignant, and malignant diseases affecting the female reproductive tract. Advances in molecular genetics, biomarker discovery, and tumor classification have fundamentally changed the diagnostic approach to many gynecologic neoplasms.

This Presidential Edition course provides a practical framework for integrating morphology, immunohistochemistry, and molecular testing into routine diagnostic practice. Faculty emphasize clinically relevant updates and diagnostic pitfalls while addressing the latest WHO classifications and consensus recommendations.

Participants gain the knowledge required to improve diagnostic accuracy, facilitate multidisciplinary patient management, and confidently evaluate both common and rare gynecologic lesions.

Target Audience

This course is designed for:

Pathologists

• Academic Pathologists

• Community Pathologists

• Gynecologic Pathologists

• Cytopathologists

Trainees

• Pathology Residents

• Surgical Pathology Fellows

• Gynecologic Pathology Fellows

Clinicians

• Gynecologic Oncologists

• Women’s Health Specialists

• Researchers in Gynecologic Disease

Learning Objectives

Upon completion of this course, participants should be able to:

• Recognize updated disease classifications and diagnostic criteria

• Identify uncommon but clinically significant gynecologic disease entities

• Apply immunohistochemical markers appropriately

• Integrate molecular genetic findings into diagnosis

• Distinguish challenging differential diagnoses

• Understand clinical implications of diagnostic findings

• Improve diagnostic precision in gynecologic pathology

• Apply updated WHO and consensus guidelines in daily practice

Updates in Gynecological Tumor Classification

WHO Classification Updates

Topics Covered

• Newly Defined Disease Entities

• Revised Diagnostic Criteria

• Emerging Classification Systems

• Consensus Recommendations

• Molecularly Defined Tumors

Diagnostic Implications

Areas Covered

• Morphologic Correlation

• Clinical Relevance

• Reporting Standards

• Prognostic Significance

Endometrial Pathology

Endometrial Hyperplasia and Carcinoma

Topics Include

• Classification Systems

• Molecular Subtypes

• Histologic Variants

• Diagnostic Pitfalls

• Ancillary Testing

Molecular Classification of Endometrial Cancer

Areas Covered

• POLE-Mutated Tumors

• Mismatch Repair Deficiency

• p53-Abnormal Tumors

• Clinical Applications

• Prognostic Stratification

Ovarian Pathology

Epithelial Ovarian Tumors

Topics Covered

• Serous Neoplasms

• Endometrioid Tumors

• Clear Cell Carcinoma

• Mucinous Tumors

• Borderline Tumors

Rare Ovarian Neoplasms

Areas Covered

• Sex Cord-Stromal Tumors

• Germ Cell Tumors

• Metastatic Tumors

• Diagnostic Challenges

Cervical Pathology

HPV-Associated and HPV-Independent Lesions

Topics Include

• Squamous Intraepithelial Lesions

• Cervical Adenocarcinoma

• HPV Testing

• Biomarker Utilization

• Differential Diagnosis

Precancerous Lesions

Areas Covered

• Histopathologic Evaluation

• Screening Correlation

• Risk Assessment

• Management Implications

Vulvar and Vaginal Pathology

Diagnostic Evaluation

Topics Covered

• Vulvar Intraepithelial Neoplasia

• Squamous Cell Carcinoma

• HPV-Related Lesions

• Non-HPV Neoplasms

• Rare Tumors

Gestational Trophoblastic Disease

Diagnostic Criteria and Classification

Topics Include

• Hydatidiform Mole

• Choriocarcinoma

• Trophoblastic Tumors

• Molecular Studies

• Clinical Correlation

Immunohistochemistry in Gynecologic Pathology

Practical Diagnostic Applications

Topics Covered

• Differential Diagnosis Strategies

• Tumor Classification

• Biomarker Selection

• Interpretation Pitfalls

• Reporting Considerations

Frequently Used Markers

Areas Covered

• p16

• p53

• ER and PR

• WT1

• Napsin A

• MMR Proteins

• Additional Diagnostic Biomarkers

Molecular Pathology

Genomic and Molecular Testing

Topics Include

• Next-Generation Sequencing

• Molecular Classification

• Targeted Therapies

• Predictive Biomarkers

• Precision Oncology

Clinical Integration

Areas Covered

• Therapeutic Implications

• Personalized Medicine

• Prognostic Assessment

• Multidisciplinary Care

Challenging Cases and Diagnostic Pitfalls

Case-Based Learning

Participants review:

• Difficult Differential Diagnoses

• Rare Gynecologic Tumors

• Histologic Mimics

• Ancillary Test Interpretation

• Real-World Diagnostic Scenarios

Clinical Correlation

Pathology and Patient Management

Topics Covered

• Surgical Planning

• Oncologic Treatment Decisions

• Prognostic Reporting

• Multidisciplinary Communication

• Personalized Care Strategies

Educational Highlights

Expert International Faculty

Presented by leading authorities in gynecologic pathology from USCAP and ISGyP.

WHO Classification Updates

Incorporates the latest evidence supporting upcoming WHO revisions.

Practical Diagnostic Focus

Emphasizes real-world diagnostic application rather than purely theoretical discussions.

Integrated Molecular Pathology

Combines morphology, immunohistochemistry, and molecular genetics for modern diagnostic practice.

Why This Course Stands Out

✔ Official USCAP Presidential Edition Program

✔ Collaboration with ISGyP Experts

✔ Updated WHO Classification Review

✔ Comprehensive Gynecologic Pathology Coverage

✔ Molecular Pathology Integration

✔ Practical Immunohistochemistry Applications

✔ Endometrial and Ovarian Tumor Updates

✔ Cervical Pathology and HPV-Related Disease

✔ Rare Tumor Recognition

✔ Diagnostic Pitfalls and Challenging Cases

✔ Evidence-Based Clinical Correlation

✔ Advanced Case-Based Learning

Who Should Take This Course?

Ideal for:

• Practicing Surgical Pathologists

• Gynecologic Pathologists

• Pathology Residents and Fellows

• Cytopathologists

• Gynecologic Oncologists

• Academic Faculty and Researchers

Clinical & Educational Value

The USCAP Gynecological Pathology: Essential Knowledge for Diagnostic Practice (Presidential Edition) 2026 provides a comprehensive and highly practical review of modern gynecologic pathology. By integrating morphology, immunohistochemistry, molecular genetics, and emerging disease classifications, the course equips participants with the diagnostic tools necessary to navigate the rapidly evolving field and improve patient outcomes.

+ Topics:

• Epithelial Neoplasms of the Uterine Corpus – Xavier N. Matias-Guiu, MD
• Squamous Lesions of the Cervix, Vagina, and Vulva – C. Blake Gilks, MD, PhD
• Gestational Trophoblastic Disease, Sex Cord-Stromal, and Germ Cell Tumors of the Ovary – Pei Hui, MD, PhD
• Mesenchymal Tumors of the Uterine Corpus – Jennifer A. Bennett, MD
• Epithelial Neoplasms of the Ovary – C. Simon Herrington, MD, PhD
• Glandular Lesions of the Cervix, Vagina, and Vulva – Takako Kiyokawa, MD
• FREE SECTION: Panel Discussion