Mayo Clinic’s 9th Annual Hematology/Oncology Case-Based Approaches to Patient Care for Advanced Practice Providers and Nurses 2026

Practical Case-Based Hematology & Oncology Education for Advanced Practice Providers and Nurses

The Mayo Clinic’s 9th Annual Hematology/Oncology Case-Based Approaches to Patient Care for Advanced Practice Providers and Nurses 2026 is a comprehensive educational program designed to enhance the clinical knowledge and decision-making skills of healthcare professionals caring for patients with hematologic and oncologic malignancies. Through a highly interactive, case-based learning format, participants gain practical strategies for diagnosis, treatment selection, supportive care, and management of treatment-related complications across a broad spectrum of cancers.

Featuring Live Recording Videos and PDFs, this program delivers evidence-based updates and real-world clinical insights from Mayo Clinic experts, helping clinicians navigate the rapidly evolving landscape of modern cancer care.

Course Overview

Cancer treatment continues to advance rapidly with the introduction of novel immunotherapies, targeted agents, cellular therapies, and personalized treatment approaches. Advanced practice providers and nurses play a critical role in patient education, treatment monitoring, toxicity management, and multidisciplinary care coordination.

This course focuses on practical clinical scenarios commonly encountered in oncology practice, helping participants improve patient outcomes through evidence-based treatment decisions, supportive care strategies, and interdisciplinary collaboration.

Using a case-based approach, faculty guide learners through complex patient presentations, treatment planning, adverse event management, and survivorship considerations.

Learning Objectives

Upon completion of this activity, participants will be able to:

• Differentiate between immunotherapy, targeted therapy, chemotherapy, and radiation therapy.
• Select appropriate treatment strategies based on cancer type, stage, and patient-specific factors.
• Apply current evidence-based recommendations for hematologic and oncologic malignancies.
• Assess patient eligibility for bone marrow transplantation.
• Evaluate indications and clinical applications of CAR T-cell therapy.
• Incorporate supportive and palliative care principles into comprehensive cancer management.
• Recognize common toxicities associated with cancer therapies.
• Implement evidence-based management strategies for treatment-related adverse effects.
• Improve interdisciplinary communication and collaborative oncology care.
• Enhance clinical decision-making through case-based problem solving.

Key Topics Covered

Hematologic Malignancies

Participants review:

• Leukemia
• Lymphoma
• Multiple myeloma
• Myelodysplastic syndromes (MDS)
• Bone marrow disorders
• Emerging hematologic therapies

Faculty discuss contemporary treatment strategies and evolving standards of care.

Solid Tumor Oncology

Coverage includes:

• Common solid tumors
• Treatment selection
• Disease staging
• Multidisciplinary management
• Personalized treatment planning
• Long-term monitoring

Participants gain practical approaches to managing complex oncology patients.

Immunotherapy

Topics include:

• Immune checkpoint inhibitors
• Mechanisms of action
• Patient selection
• Immune-related adverse events
• Toxicity recognition
• Management algorithms

Special emphasis is placed on real-world management of immunotherapy complications.

Targeted Therapy

Sessions focus on:

• Molecularly targeted treatments
• Precision oncology
• Biomarker-driven therapies
• Treatment monitoring
• Resistance mechanisms
• Toxicity management

Participants learn how targeted therapies are integrated into modern cancer care.

Chemotherapy & Radiation Therapy

Coverage includes:

• Conventional chemotherapy principles
• Radiation treatment approaches
• Treatment sequencing
• Combination therapy strategies
• Adverse effect management
• Patient education considerations

The course reviews practical considerations for daily oncology practice.

Bone Marrow Transplantation

Topics include:

• Indications for transplantation
• Patient eligibility assessment
• Pre-transplant evaluation
• Post-transplant monitoring
• Complication management
• Long-term follow-up

Participants gain a better understanding of transplant referral and patient management.

CAR T-Cell Therapy

Sessions address:

• Cellular immunotherapy fundamentals
• Patient selection
• Treatment pathways
• Cytokine release syndrome (CRS)
• Neurotoxicity management
• Follow-up care

Faculty discuss the expanding role of CAR T-cell therapy in hematologic malignancies.

Supportive & Palliative Care

Key topics include:

• Symptom management
• Cancer-related fatigue
• Pain management
• Nutritional support
• Psychosocial care
• Quality-of-life optimization

The course emphasizes patient-centered cancer care throughout the disease continuum.

Treatment Toxicity Management

Participants review:

• Immunotherapy-related toxicities
• Chemotherapy complications
• Targeted therapy adverse effects
• Radiation-related complications
• Supportive treatment interventions
• Clinical practice guidelines

Case-Based Clinical Decision Making

Through interactive cases, participants learn:

• Diagnostic reasoning
• Treatment selection
• Multidisciplinary coordination
• Management of complex oncology scenarios
• Evidence-based clinical problem solving

Educational Features

✔ Case-Based Learning Format

✔ Mayo Clinic Faculty

✔ Practical Oncology Updates

✔ Real-World Clinical Scenarios

✔ Evidence-Based Treatment Strategies

✔ Immunotherapy & CAR T Updates

✔ Supportive Care Integration

✔ Multidisciplinary Cancer Management

✔ Advanced Practice Provider Focus

✔ Immediate Clinical Application

Target Audience

This course is ideal for:

• Nurse Practitioners (NPs)
• Physician Assistants (PAs)
• Oncology Nurses
• Hematology Nurses
• Medical Oncologists
• Hematologists
• Internal Medicine Physicians
• Pharmacists
• Residents & Fellows
• Advanced Practice Providers in Oncology

Why This Course Stands Out

✔ Specifically designed for advanced practice providers and nurses

✔ Strong emphasis on practical patient management

✔ Comprehensive review of hematology and oncology topics

✔ Detailed coverage of immunotherapy and CAR T-cell therapy

✔ Focus on treatment-related toxicity management

✔ Interactive case-based teaching format

✔ Evidence-based clinical recommendations

✔ Emphasis on multidisciplinary cancer care

✔ Applicable to both inpatient and outpatient oncology practice

✔ Led by Mayo Clinic oncology experts

Clinical Value

The Mayo Clinic’s 9th Annual Hematology/Oncology Case-Based Approaches to Patient Care for Advanced Practice Providers and Nurses 2026 provides a practical and comprehensive review of modern cancer care. Covering hematologic malignancies, solid tumors, immunotherapy, targeted therapy, chemotherapy, radiation therapy, bone marrow transplantation, CAR T-cell therapy, and supportive care, this program equips clinicians with the knowledge and skills needed to deliver high-quality, evidence-based oncology care.