SSRP Mastermind 10: Post-Viral Fatigue 2023

Advanced Cellular Medicine, Long COVID, Chronic Fatigue Syndrome & Immunometabolic Recovery

The Seeds Scientific Research & Performance (SSRP) Mastermind 10: Post-Viral Fatigue 2023 delivers an advanced exploration of the cellular, immunological, and metabolic mechanisms underlying post-viral fatigue syndromes. Designed for clinicians managing complex chronic illnesses, this educational program examines how persistent immune activation, mitochondrial dysfunction, neuroinflammation, and impaired cellular recovery contribute to long-term symptoms following viral infections.

Using a mechanism-first approach rooted in cellular medicine, the course provides a comprehensive framework for understanding conditions such as Long COVID, Chronic Fatigue Syndrome (ME/CFS), Epstein-Barr virus reactivation, and other post-infectious fatigue syndromes. Faculty explore the intersection of immunology, metabolism, redox biology, peptide therapeutics, and inflammation-resolution pathways to help clinicians develop more precise and individualized treatment strategies.

Through in-depth lectures, clinical reasoning models, and practical therapeutic discussions, participants learn how to identify key biological drivers of persistent fatigue and implement evidence-informed recovery protocols for complex patients.

Product Details

Format: 7 Videos (.mp4) + 7 Subtitle Files (.vtt) + 7 PDFs

Duration: 10+ Hours

Modules: 2

Lessons: 7

Access: On-Demand

Educational Provider: SSRP (Seeds Scientific Research & Performance)

Program Overview

Post-viral fatigue has emerged as a major healthcare challenge following the COVID-19 pandemic, but similar syndromes have long been observed after infections such as:

• Epstein-Barr Virus (EBV)
• Cytomegalovirus (CMV)
• Dengue Fever
• West Nile Virus
• Influenza
• SARS
• Other viral illnesses

This program examines why some patients recover fully while others experience persistent symptoms including:

• Chronic fatigue
• Cognitive dysfunction (“brain fog”)
• Exercise intolerance
• Sleep disturbances
• Dysautonomia
• Chronic inflammation
• Immune dysregulation

Participants learn how these symptoms may be linked to abnormalities in cellular energy production, immune signaling, mitochondrial function, and inflammatory resolution pathways.

Learning Objectives

Upon completion of this activity, participants will be able to:

• Understand the cellular mechanisms involved in post-viral fatigue syndromes.
• Analyze immune signaling pathways associated with chronic inflammation and viral persistence.
• Evaluate mitochondrial dysfunction and its role in impaired energy production.
• Apply peptide-based and targeted therapeutic strategies in complex chronic illness.
• Assess neuroinflammatory processes contributing to cognitive dysfunction and fatigue.
• Utilize specialized pro-resolving mediators (SPMs) to support inflammatory resolution.
• Identify factors associated with latent viral reactivation.
• Develop personalized recovery protocols based on immunometabolic principles.

Immunometabolism & Chronic Inflammation

A major focus of the course is understanding how chronic immune activation disrupts cellular function following viral illness.

Topics include:

• Cytokine signaling
• Interferon pathways
• Chronic inflammatory states
• Immune dysregulation
• Persistent immune activation
• Oxidative stress
• Cellular stress responses

Faculty explain how prolonged inflammation can contribute to fatigue, impaired recovery, and multisystem dysfunction.

cGAS–STING Pathway & Immune Signaling

The program explores one of the most important emerging areas in modern immunology.

Coverage includes:

• cGAS–STING signaling
• Innate immune activation
• Viral sensing mechanisms
• Interferon production
• Immune system regulation
• Chronic inflammatory activation
• Cellular danger signals

Participants gain insight into how dysregulated immune signaling may contribute to ongoing symptoms after viral infections.

Mitochondrial Dysfunction & Cellular Energy Failure

One of the central themes of the course is the role of mitochondria in post-viral recovery.

Topics include:

• ATP production
• Mitochondrial stress
• Cellular bioenergetics
• Energy metabolism
• Fatigue physiology
• Oxidative phosphorylation
• Recovery pathways

Faculty discuss how impaired mitochondrial function may lead to persistent fatigue and exercise intolerance.

Long COVID & Chronic Fatigue Syndrome

The course reviews contemporary theories regarding:

• Long COVID
• Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
• Post-infectious syndromes
• Neuroimmune dysfunction
• Persistent symptom complexes

Participants learn how modern cellular medicine frameworks attempt to explain these challenging conditions.

Neuroinflammation & Cognitive Dysfunction

Many post-viral patients experience neurological symptoms.

Topics include:

• Brain fog
• Neuroinflammation
• Microglial activation
• Cognitive dysfunction
• Memory impairment
• Neuroimmune signaling
• Central nervous system inflammation

Faculty review potential biological mechanisms contributing to persistent neurological symptoms.

Specialized Pro-Resolving Mediators (SPMs)

The program examines how the body naturally resolves inflammation.

Topics include:

• Resolution biology
• Omega-3 signaling pathways
• Omega-6 lipid mediators
• Inflammatory resolution
• Tissue recovery
• Immune regulation

Participants explore how SPMs may support restoration of normal immune function.

Peptide Therapies & Cellular Interventions

The course discusses emerging peptide-based approaches commonly used in cellular and integrative medicine.

Coverage includes:

• LL-37
• Thymosin Alpha-1 (TA-1)
• Immune-modulating peptides
• Cellular signaling
• Clinical implementation considerations
• Regulatory considerations
• Adjunctive treatment strategies

Faculty focus on the scientific rationale behind these therapies and their proposed clinical applications.

Environmental & Infectious Triggers

Additional discussions examine factors that may perpetuate chronic symptoms.

Topics include:

• Viral reactivation
• Epstein-Barr Virus
• Environmental exposures
• Mold-related illness
• Chronic microbial triggers
• Immune burden
• Host resilience factors

Participants learn how multiple stressors may contribute to prolonged recovery.

Target Audience

This course is ideal for:

• Integrative Medicine Physicians
• Functional Medicine Practitioners
• Immunologists
• Internal Medicine Physicians
• Anti-Aging & Longevity Specialists
• Family Medicine Physicians
• Nurse Practitioners
• Physician Assistants
• Healthcare Professionals Managing Complex Chronic Illness